Everything about ceesdekker.net
Everything about ceesdekker.net
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As a human being, I hold the biblical assignment to take a look at and use every little thing in development for the good thing about my neighbour. I do not expertise any conflict involving faith and science. Quite the opposite, my religion stimulates me to complete science, for being open-minded on the earth.’
2007, first real-time detection of strand exchange in homologous recombination by RecA; discovery of the low persistence length of finishes of microtubules; and fixed the mechanism of biosensing with carbon nanotubes
2015, discovery that condensin is a really versatile protein structure; and to start with detection of DNA knots working with nanopores
Immediate immobilization of native yeast iso-one cytochrome c on bare gold: rapidly electron relay to redox enzymes and zeptomole protein-movie voltammetry
MATLAB codes for info processing can be found at . Julia codes used for numerical simulation can be obtained at .
Movement-pushed rotary motors which include windmills and h2o wheels drive practical procedures in human Modern society. Whilst examples of such rotary https://www.ceesdekker.net motors also function prominently in cell biology, their synthetic building with the nanoscale has remained challenging. Here we show circulation-pushed rotary movement of the self-arranged DNA nanostructure that is definitely docked on to a nanopore in a skinny stable-point out membrane. An elastic DNA bundle self-assembles right into a chiral conformation on phoretic docking on to the stable-point out nanopore, and subsequently shows a sustained unidirectional rotary movement of up to twenty rev s−1.
2003, shown the main biosensors designed away from a carbon nanotube; settled the construction and mechanism of DNA repair proteins; and discovery of a brand new technique for fabricating good-point out nanopores for DNA translocation
1). The existing–voltage curves showed major modulations with gate voltage, even at room temperature, which was in keeping with band bending within a ~0.six eV bandgap semiconducting nanotube. These information also confirmed that the conductance may be modulated by six orders of magnitude by modifying the gate voltage. The outcomes of the work — a area-temperature transistor made from an individual carbon nanotube molecule — were being printed in Mother nature in May 1998.
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial mobile division
2006, initial demonstration of molecular sorting in a very lab with a chip making use of biomotors; discovery of nanobubbles in good-state nanopores; and very first estimate of electrokinetic Electrical power conversion inside a nanofluidic channel
Enable’s to start with look back in the intervening time after you decided to shift your concentrate from superconductivity and nanotubes to biology at the end of the nineties.
Supercoiling-dependent DNA binding: quantitative modeling and apps to bulk and solitary-molecule experiments